Review published on March 16, 2017.
Genes are not only the key to life, but holds the details of our history and our future too. In this book, Mukherjee takes us on a journey to uncover the origins of this master code and the story of discovering and deciphering it. It is a story that spans world history, but begins with a monk in an Augustinian monastery who discovers a unit of heredity in his study of peas. Mendel may not have been one of the first to be fascinated but the ideas of heredity, and he certainly wasn’t going to be the last. Darwin was one of the next with his discovery of evolution and the way that certain traits established themselves in the populations of finches on each of the Galapagos Islands.
He is eminently qualified to write this, as he is the assistant professor of medicine at Columbia University. He brings us up to date with the latest research and discoveries in genetic research as well as posing the questions that we need to ask and answer as we learn how to change and write to the human genome. To cover all that we have found out about the gene, the book needs to be broad in scope. It is fairly detailed and occasionally baffling and incomprehensible to a non-scientist like myself, but thankfully not very often. Woven through the book too is the story of Mukherjee’s family and their reoccurring history of mental illness as it moved through the generations; it adds a nice personal touch to the book, showing just how our genes can affect us all. If you want a good overview of the history of the gene, you can’t go wrong starting here.
Paul Cheney 4*
The Gene: An Intimate History by Siddhartha Mukherjee, published on 23 March, 2017 by Vintage in paperback
Shortlisted for the Wellcome Book Prize 2017
Wellcome Book Prize 2017 shortlist: When Breath Becomes Air by Paul Kalanithi